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Omeprazole and esomeprazole. High dose omeprazole (80mg daily) has been shown to reduce the maximum plasma levels of clopidogrel by 49%.
omeprazole infusion (Hong Kong Protocol), initial 80 mg dose (give 80mg in omeprazole oral 40mg twice daily for 2 weeks then 40mg daily for 6 weeks.
If the patient is unable to take oral therapy give: omeprazole 40mg by omeprazole infusion (Hong Kong Protocol), initial 80 mg dose (give 80mg in
JY Lau et al 2024. HKSAR, 638 GIB patients divided into two groups before endoscopy, omeprazole (bolus of 80mg omeprazole followed by infusion
omeprazole infusion (Hong Kong Protocol), initial 80 mg dose (give 80mg in omeprazole oral 40mg twice daily for 2 weeks then 40mg daily for 6 weeks.
In one treatment period subjects were given omeprazole (80mg/day) alone for omeprazole at different times does not prevent this interaction (Table 1).
Omeprazole and esomeprazole. High dose omeprazole (80mg daily) has been shown to reduce the maximum plasma levels of clopidogrel by 49
Omeprazole and esomeprazole. High dose omeprazole (80mg daily) has been shown to reduce the maximum plasma levels of clopidogrel by 49%. Lower
Hence Omeprazole being a much more expensive drug than it is now.....