anaerobic bacteria. Clinicians depend heavily on information from the Remove the meropenem disk from each TSB-meropenem disk suspension using a 10
Indications and dose For meropenem Aerobic and anaerobic Gram-positive and Gram-negative infections, Hospital-acquired septicaemia for meropenem By intravenous infusion, or by intravenous injection
TABLE OF CONTENTS If nosocomial – treat as HAP, with preference for Piperacillin/Tazobactam, Imipenem or Meropenem for anaerobic coverage, or add Clindamycin
Antimicrobial agents with broader coverage against anaerobic bacteria, including peptostreptococci, include cefoxitin, clindamycin, carbapenem (eg, imipenem, meropenem, ertapenem, doripenem), tigecycline, the combination of a penicillin (eg, ticarcillin) with a beta-lactamase inhibitor (ie, clavulanate), and quinolones with anti-anaerobic
Carbapenems (meropenem, ertapenem, imipenem). Metronidazole. Clindamycin Double trouble: how big a problem is redundant anaerobic antibiotic coverage in
Routine addition of anaerobic coverage for suspected aspiration pneumonia is not recommended unless Meropenem 1 g IV q8h (step down to cipro if
Clindamycin can be useful for lung abscess, due to combined coverage of anaerobes and oral streptococcal spp. Carbapenem ( Meropenem; imipenem/
meropenem) have anaerobic cover so metronidazole is not needed. Temocillin aztreonam have no anaerobic or gram positive cover. Carbapenem - resistant
Meropenem. Excellent broad spectrum (Gram-positive, Gram-negative, and anaerobe) coverage; would reserve for seriously ill patients. Will cover
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